If you suffer from severe pain at the ball of the feet from metatarsalgia as well as neuroma and heel pain, you may be suffering from fat pad atrophy. In this situation the fat pad from your area of the pain in the bottom of your foot has decreased. This results in increased pain at the ball of the feet because the bones are now hitting the ground with increased pressure because the fat pad cushion has subsided. Sometimes you may have a lesion at the fifth toe or a corn or callus at the ball of the feet which is very very painful. These are painful because of the fat pad atrophy in those particular areas as well. At the Comprehensive Foot and Ankle Institute we use regenerative medical therapy to help overcome this problem. We inject Liposana which is adipose tissue that will help augment and cushion the particular area where there is pain.